I'd say it's about 50/50 as to whether the fix means anything or its just random. Lately, with all the new GPS/RNAV approaches being developed they're starting to run out of pronounceable words to use so they tend to elect function over form.
I came across an interesting
article on this subject in which the author, "I identified a number of word categories, which give you some hint about the kinds of people who are making up the words."
Sports fanatics: Near Boston, you have CELTS and BOSOX. Only in Texas you find: GOALL, PPUNT, DRPPD, FTBAL,TEXNN, COACH, QTRBK, TAKKL, RECVR, FMBLE and TCHDN. By Soldier Field; KUBBS and BEARS. In DC GIBBZ, SKINS, and MONKK. In Portland, the pair of TRAYL and BLAZR, balanced by the highbrow OMMSI,(Portland's Oregon Museum of Science & Industry) and POWLZ (the incredible Powell's Bookstore).
Foodies: Near Kansas City, you get the regional SPICY, BARBQ, TERKY, SMOKE and RIBBS. And in Vermont and New Hampshire, HAMMM BURGR FRYYS
Guys or maybe Girls (I’m guessing the names are for girlfriends): SUSAN, SUSIE, SUSIQ, SUZAN, SUZEE, SUZEY, SUZIE, SUZIQ, SUZYQ, SUZYY, LIZIE, LIZZE, LIZZY, LIZZZ, ANNEE, ANNEY, ANNNE, ANNII, ANNYE.
Political junkies: By Andrews Air Force Base, you find DUBYA, BUUSH, FORRD, RREGN. No Democrats so far.