Dan, UPS flies a 757 in and out of BUF. Fedex still uses the 727 for BUF routes.
Each airport individual airport has their own unofficial practice area, as Peter stated. For example, Akron's practice area starts at a point about 5nm north of the airport and is concentrated over what we call "the swamps" near the Iriquois Wildlife Reserve. It actually extends up to Middleport and Medina. However, remember, it's unofficial.
BUF's is in a similar area, but a little further north of Akron's. There's actually a little overlap to the point when we're talking to BUF, we'll get traffic reports of one of Prior's Warriors in the area.
The Buffalo Airfield, in West Seneca, has a practice area between Hamburg and Angola right along the lake shore. It's starts as you proceed SW of Bills Stadium. The stadium is kind of the informal checkpoint for the end of the Class C shelf (when you can start climbing above 2200 feet).
Hope this helps,